[Study on the alkaloids constituents from Voacanga africana].

Abstract

OBJECTIVE: To study the alkaloids of Voacanga africana. METHODS: The alkaloids were isolated by normal phase silica gel and Sephadex LH-20 column chromatography. Their structures were elucidated by analysis of spectroscopic data. RESULTS: Eight alkaloids were isolated and their structures were elucidated as voacangine(1), voacangine hydroxyindolenine(2), 19R-epi-voacristine(3), epi-ibogaine(4), vobasine(5), 19-epi-heyneanine(6), vobtusine(7) and voacamine(8). CONCLUSION: Compounds 2-4 and 6 are isolated from this plant for the first time.

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