Serotonergic Hallucinogens and Emerging Targets for Addiction Pharmacotherapies

Abstract

Hallucinogens are a broad group of drugs that are narrowly defined in the DSM-IV1 to include only: However, they more broadly can include: Most hallucinogens are included in the schedule I category as originally defined by the Controlled Substances Act of 1970.2 As such, by definition they are classified as having no currently accepted medical use in the United States, lacking in safety for use under medical supervision, and possessing high addictive liability. From an addiction perspective, it is worth examining the evidence base for this classification to understand the true addictive liability of this class of agents.

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