Non-Amphetaminic Central Stimulation by Alkaloids from the Ibogane and Vobasine Series

Abstract

Ibogane alkaloids were shown to have a very high arousal activity. Similarly, a stimulating CNS activity was demonstrated for vobasine alkaloids. The influence of certain substituents was evidenced: a methoxy substituent increases the activity, while it is lowered by a methoxycarbonyl substituent.

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