Methods for the detection and determination of ibogaine in biological materials.

Abstract

Ibogaine is a psychotropic alkaloid belonging to the indole group, originally obtained from the West African shrub Tabernanthe Iboga (fam. Apocynaceae) (1). It was first isolated by Dybowski and Landrin in 1901 (2). The formula suggested by Taylor et al. (3) for this compound has been confirmed by X-ray crystallography (4) (Fig.1)

The extensive use of psychotropic drugs in modern therapy has created problems in the field of law enforcement. Traffic offenses are believed to occur with increased frequency especially when such drugs are taken with alcohol. Ibogaine has been reported to be used by addicts (5).

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