Alkaloids from leaves and root bark of Ervatamia hirta

Abstract

During chemical investigation of the leaves and root bark ofErvatamia hirta, 33 alkaloids were isolated. Seven are new: six are the ‘monomeric’ alkaloids (E) 16-epi-normacusineB, (E) 16-epi-affinisine,O-acetyl-16-epi-affinisine, affinisine-N(4)-oxide, dehydro-16-epi-affinisine, norfluorocurarine-N(4)-oxide, and the seventh is the bisindole 16-decarbomethoxyvoacamine-pseudoindoxyl. The known alkaloids are: (E) 16-epi-isositsirikine, β-yohimbine, yohimbine, 19,20-dehydro-β-yohimbine, β-yohimbine-pseudoindoxyl, isositsirikine, 19,20-dihydroisositsirikine, β-yohimbine-oxindole, normacusineB, affinisine, vobasine, dregamine, tabernaemontanine, norfluorocurarine, 12-hydroxynorfluorocurarine, apparicine, 3,14-dihydroellipticine, antirhine, voacristine, ibogaine, i☐ygaine, i☐ygaine-hydroxyindolenine, iboluteine, 4′,17,(17β)-dihydrotchibangensine, 16-decarbomethoxyvoacamine and 19,20-dihydro-16-decarbomethoxyvoacamine. Structural elucidation of the new alkaloids is based on spectral data and chemical correlations.

Sources

0 Comments

Leave a reply

Your email address will not be published. Required fields are marked *

*

©2012-2019 Global Ibogaine Therapy Alliance - Privacy Policy - Contact Us

or

Log in with your credentials

or    

Forgot your details?

or

Create Account