Pharmacology Archives - The Global Ibogaine Therapy Alliance

GDNF is a fast-acting potent inhibitor of alcohol consumption and relapse

Authors: S. Carnicella, V. Kharazia, J. Jeanblanc, P. H. Janak, D. Ron
Published: Proceedings of the National Academy of Sciences
Date: 9 June 2008
Category:Medicine, Pharmacology
Tags:addiction treatment, alcohol, GDNF
Comments:0

Ibogaine, an anti-addictive drug: pharmacology and time to go further in development. A narrative review

Authors: R Maciulaitis, V Kontrimaviciute, F. Bressolle, V Briedis
Published: Human & Experimental Toxicology
Date: 1 March 2008
Category:Medicine, Literature Review, Pharmacology
Tags:addiction treatment, mechanism of action
Comments:0

The plant alkaloid voacamine induces apoptosis-independent autophagic cell death on both sensitive and multidrug resistant human osteosarcoma cells.

Authors: Meschini S, Condello M, Calcabrini A, Marra M, Formisano G, Lista P, De Milito A, Federici E, Arancia G
Published: Autophagy
Date: November 2008
Category:Medicine, Pharmacology
Tags:voacamine
Comments:0

18-Methoxycoronaridine blocks acquisition but enhances reinstatement of a cocaine place preference

Authors: Sarah E. McCallum, Stanley D. Glick
Published: Neuroscience Letters
Date: July 2009
Category:Medicine, Pharmacology, Clinical Trials
Tags:18-mc, addiction treatment, animal models, cocaine, place preference
Comments:0

Induction of energy metabolism related enzymes in yeast Saccharomyces cerevisiae exposed to ibogaine is adaptation to acute decrease in ATP energy pool

Authors: Roman Paškulin, Polona Jamnik, Nataša Obermajer, Marija Slavić, Borut Štrukelj
Published: European Journal of Pharmacology
Date: February 2010
Category:Medicine, Pharmacology
Tags:ATP, metabolism, stress
Comments:0

Interaction of drugs of abuse and maintenance treatments with human P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2)

Authors: Nicolas Tournier, Lucie Chevillard, Bruno Megarbane, Stéphane Pirnay, Jean-Michel Scherrmann, Xavier Declèves
Published: The International Journal of Neuropsychopharmacology
Date: 3 November 2009
Category:Medicine, Pharmacology
Tags:buprenorphine, methadone
Comments:0

Interaction of 18-methoxycoronaridine with nicotinic acetylcholine receptors in different conformational states

Authors: Hugo R. Arias, Avraham Rosenberg, Dominik Feuerbach, Katarzyna M. Targowska-Duda, Ryszard Maciejewski, Krzysztof Jozwiak, Ruin Moaddel, Stanley D. Glick, Irving W. Wainer
Published: Biochimica et Biophysica Acta (BBA) - Biomembranes
Date: June 2010
Category:Neurochemistry, Medicine, Pharmacology
Tags:18-mc, acetylcholine, nicotine
Comments:0

Catharanthine alkaloids are noncompetitive antagonists of muscle-type nicotinic acetylcholine receptors

Authors: Hugo R. Arias, Dominik Feuerbach, Katarzyna M. Targowska-Duda, Krzysztof Jozwiak
Published: Neurochemistry International
Date: 2010,9
Category:Neurochemistry, Medicine, Pharmacology
Tags:acetylcholine, catharanthine, mechanism of action, nicotine
Comments:0

Interaction of ibogaine with human α3β4-nicotinic acetylcholine receptors in different conformational states

Authors: Hugo R. Arias, Avraham Rosenberg, Katarzyna M. Targowska-Duda, Dominik Feuerbach, Xiao Juan Yuan, Krzysztof Jozwiak, Ruin Moaddel, Irving W. Wainer
Published: The International Journal of Biochemistry & Cell Biology
Date: September 2010
Category:Neurochemistry, Medicine, Pharmacology
Tags:mechanism of action
Comments:0

Synthesis and Resolution of cis -(±)-Methyl (1 R ,2 S /1 S ,2 R )-2-[(4-Hydroxy-4-phenylpiperidin-1-yl)methyl]-1-(4-methylphenyl)cyclopropanecarboxylate [(±)-PPCC)]: New σ Receptor Ligands with Neuroprotective Effect

Authors: Orazio Prezzavento, Agata Campisi, Carmela Parenti, Simone Ronsisvalle, Giuseppina Aricò, Emanuela Arena, Marco Pistolozzi, Giovanna M. Scoto, Carlo Bertucci, Angelo Vanella, Giuseppe Ronsisvalle
Published: Journal of Medicinal Chemistry
Date: 12 August 2010
Category:Neurochemistry, Medicine, Pharmacology
Tags:k-opioid receptor
Comments:0

Resistance of male Sprague–Dawley rats to sucrose-induced obesity: Effects of 18-methoxycoronaridine

Authors: Olga D. Taraschenko, Isabelle M. Maisonneuve, Stanley D. Glick
Published: Physiology & Behavior
Date: February 2011
Category:Medicine, Pharmacology, Clinical Trials
Tags:18-mc, animal models, obesity
Comments:0

Noribogaine, but not 18-MC, exhibits similar actions as ibogaine on GDNF expression and ethanol self-administration

Authors: Sebastien Carnicella, Dao-Yao He, Quinn V. Yowell, Stanley D Glick, Dorit Ron
Published: Addiction Biology
Date: October 2010
Category:Medicine, Pharmacology
Tags:18-mc, GDNF, noribogaine
Comments:0

Effects of 18-methoxycoronaridine on ghrelin-induced increases in sucrose intake and accumbal dopamine overflow in female rats

Authors: Sarah E. McCallum, Olga D. Taraschenko, Ethan R. Hathaway, Melanie Y. Vincent, Stanley D. Glick
Published: Psychopharmacology
Date: 6 January 2011
Category:Neurochemistry, Medicine, Pharmacology
Tags:18-mc, dopamine
Comments:0

Sex differences in high fat-induced obesity in rats: Effects of 18-methoxycoronaridine

Authors: unknown
Published: Physiology & Behavior
Date: July 2011
Category:Medicine, Pharmacology, Clinical Trials
Tags:18-mc, gender, nicotine, obesity
Comments:0

A natural small molecule voacangine inhibits angiogenesis both in vitro and in vivo

Authors: Yonghyo Kim, Hye Jin Jung, Ho Jeong Kwon
Published: Biochemical and Biophysical Research Communications
Date: January 2012
Category:Medicine, Pharmacology
Tags:angiogenesis, cancer, voacangine
Comments:0

Pharmacology

GDNF is a fast-acting potent inhibitor of alcohol consumption and relapse

Ibogaine, an anti-addictive drug: pharmacology and time to go further in development. A narrative review

The plant alkaloid voacamine induces apoptosis-independent autophagic cell death on both sensitive and multidrug resistant human osteosarcoma cells.

18-Methoxycoronaridine blocks acquisition but enhances reinstatement of a cocaine place preference

Induction of energy metabolism related enzymes in yeast Saccharomyces cerevisiae exposed to ibogaine is adaptation to acute decrease in ATP energy pool

Interaction of drugs of abuse and maintenance treatments with human P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2)

Interaction of 18-methoxycoronaridine with nicotinic acetylcholine receptors in different conformational states

Catharanthine alkaloids are noncompetitive antagonists of muscle-type nicotinic acetylcholine receptors

Interaction of ibogaine with human α3β4-nicotinic acetylcholine receptors in different conformational states

Synthesis and Resolution of cis -(±)-Methyl (1 R ,2 S /1 S ,2 R )-2-[(4-Hydroxy-4-phenylpiperidin-1-yl)methyl]-1-(4-methylphenyl)cyclopropanecarboxylate [(±)-PPCC)]: New σ Receptor Ligands with Neuroprotective Effect

Resistance of male Sprague–Dawley rats to sucrose-induced obesity: Effects of 18-methoxycoronaridine

Noribogaine, but not 18-MC, exhibits similar actions as ibogaine on GDNF expression and ethanol self-administration

Effects of 18-methoxycoronaridine on ghrelin-induced increases in sucrose intake and accumbal dopamine overflow in female rats

Sex differences in high fat-induced obesity in rats: Effects of 18-methoxycoronaridine

A natural small molecule voacangine inhibits angiogenesis both in vitro and in vivo

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